Alkaline-Activated Enzymes Liquify Food

The Stomach acid and acid-activated enzymes combined with the Alkaline bile and pancreatic alkaline-activated enzymes plus gallbladder alkaline bile to liquify food in order for the nutrition to be extracted and absorbed.

Yes, this included the alkaline foods many are eating. Unfortunately, many are under the assumption that eating “alkaline” foods are going to make their body “Alkaline”. All food must undergo chemical breakdown to extract the nutrition from it.

This brings into question what happens when those “alkalizing” with baking soda or alkaline water. In addition to those taking Antacids (Tums, Prevacid, Gaviscon) or Acid Blocker or Proton Pump Inhibitors (PPI) Pepcid, Tagamet, Zantac are either neutralizing or stopping stomach acid production. Anyone who has ever attended a Chemistry class should know that mixing a large amount of Alkaline with an Acid dilutes and neutralizes the Acid.

When there is NO Stomach Acid caused by repeatedly ALKALIZING – There is No Release of Alkaline-Activated Pancreatic enzymes. Without these enzymes, as much as 60 per cent of the fat entering the small intestine may be unabsorbed, as well as one third to one half of the proteins and carbohydrates. As a result, large portions of the ingested food cannot be used for nutrition.

It is important that the proteolytic enzymes of the pancreatic juice not become activated until after they have been secreted into the intestine because the trypsin and the other enzymes would digest the pancreas itself.

When the stomach is repeatedly alkalized or the pancreas is damaged and/or a duct becomes blocked, large quantities of pancreatic enzymes become pooled in the damaged areas of the pancreas. Under these conditions, the effect of trypsin inhibitor is overwhelmed, in which case the pancreatic secretions rapidly become activated and can start digesting the insulin producing cells of the pancreas first, giving rise to the condition called Insulin Resistance. 

At a pH of 8.5 – 9.5, the stomach acid and acid-activated enzymes from the stomach are no longer active. The stomach acid kills the alkaline – loving bacteria, parasites and fungi. Alkaline – loving microbes cause the most serious disease conditions. The pancreas juices and bile kills the acid – loving bacteria (Acidophilus – acid / philus – loving), parasites, and fungi. This leaves the stomach, duodenum and jejunum in a virtually sterile environment with very few bacteria able to survive in that terrain.

This is how alkalinity supports the breakdown and liquefaction of food into chime.

All food must undergo chemical breakdown to extract the nutrition from it.

Chyme or chymus is the semi-fluid mass of partly digested food that is expelled by the stomach, through the pyloric valve, into the duodenum (the beginning of the small intestine). The chyme that enters the small intestine from the stomach should be acidic due to secretion of hydrochloric acid in the stomach. Acid-activated enzymes also play a role in the stomach to liquify and emulsify food.

Chyme results from the mechanical and chemical breakdown of a bolus and consists of partially digested food, water, hydrochloric acid, and acid-activated digestive enzymes produced by the stomach. Chyme slowly passes through the pyloric sphincter and into the duodenum (first part of the small intestine), where the extraction of nutrients begins. Depending on the quantity and contents of the meal, the stomach will digest the food into chyme in anywhere between 40 minutes to a few hours. In the small intestine another set of alkaline-activated enzymes from the pancreas are stimulated hormonally to be released. But only when Acid is sensed in the small intestine.

No Acid – No Release of Alkaline-Activated Pancreatic enzymes.

Guyton’s Textbook of Medical Physiology

Because these pancreatic alkaline-activated enzyme are so caustic. The body defends itself by releasing the pancreatic enzyme and bile only if food is acidic entering the small intestine.

With a pH of approximately 2, chyme emerging from the stomach is very acidic. The duodenum secretes a hormone, cholecystokinin (CCK) into the blood, which causes the gall bladder to contract, releasing alkaline bile into the duodenum. The duodenum of small intestine receives bile juice via the hepatic duct. It is secreted by the liver and stored and concentrated in the gall bladder. This contains bile salts which not only neutralize the acidic chyme but also serve other functions like emulsification of lipids and fats.

The duodenum simultaneously secretes the hormone Secretin into the blood, causes the release of digestive juices and enzymes from the pancreas. Without the proper pH of 2 diluted to a ph of ~4, the pancreatic enzymes will remain trapped in the pancreas. A single H+ cation can chain activate the enzymes within the pancreas. The 99% of the exocrine pancreatic cells that produce the enzymes are protected from the enzymes. However, the 1% of endocrine pancreas cells that produce insulin are not. The endocrine cells are constantly being damaged and destroyed by the enzymes resulting in insulin resistance symptoms. There is a constant need for their replacement.

The duodenum is a short section of the small intestine located between the stomach and the rest of the small intestine. The duodenum also produces the hormone secretin to stimulate the pancreatic secretion of large amounts of sodium bicarbonate, which then raises pH of the chyme to 8.5 to 9.5. The combination of the alkaline enzymes and the alkaline pH liquefies the bolus of food into the semi-fluid chime.

The chyme then moves through the jejunum and the ileum, where digestion and absorption progresses, and the nonuseful portion continues onward into the large intestine. The duodenum is protected by a thick layer of mucus and the neutralizing the alkaline actions of the sodium bicarbonate and bile.

This then leads into the further breakdown of the nutrients still present by anaerobic bacteria upon reaching the large intestine (colon), which at the same time help to package the remains for elimination. These bacteria also help synthesize vitamin B and vitamin K, which will be absorbed along with other nutrients.

Marc R. Yago, Adam R. Frymoyer, et. al. Gastric Reacidification with Betaine HCl in Healthy Volunteers with Rabeprazole-Induced Hypochlorhydria. Molecular Pharmaceutics 2013 10 (11), 4032-4037

After gastric pH > 4 was confirmed for 15 min, 1500 mg of betaine HCl was given orally with 90 mL of water and gastric pH was continuously monitored for 2 h. Betaine HCl significantly lowered gastric pH by 4.5 (±0.5) units from 5.2 (±0.5) to 0.6 (±0.2) (P < 0.001) during the 30 min interval after administration. The onset of effect of betaine HCl was rapid, with a mean time to pH < 3 of 6.3 (±4.3) min. The reacidification period was temporary with a gastric pH < 3 and < 4 lasting 73 (±33) and 77 (±30) min, respectively.

Alkalizing Diets Support Disease Causing Alkaline Loving Bacteria.

Disease Causing Bacteria, Parasites and Fungi Thrive in an Alkaline Environment. Alkalizing Diets Support Disease Causing Alkaline Loving Bacteria. It is a fact, that disease causing microorganisms (bacteria, parasites, and fungi) harmful to the human body grow best in an ALKALINE environment. This fact is ignored by those promoting “Alkalizing” for better health. This is particularly interesting in the light of the evidence that human beings have an instinct, which leads them to seek an acid intake.


Pathogenic Microorganism preferring an Alkaline Environment

  • Staphylococcus 7.4 – alkaline
  • Streptococcus 7.4 to 7.6 – alkaline
  • Pneumococcus 7.6 to 7.8 – alkaline
  • H. Influenza 7.8 – alkaline
  • Meningococcus 7.4 to 7.6 – alkaline
  • Gonococcus Corymbacterium diptheriae 7.2 – alkaline
  • B. abortus 7.2 to 7.4 – alkaline
  • B. tularemae 6.8 to 7.3 – alkaline
  • Clostridium tetani 7.0 to 7.6 – alkaline

In the light of the above evidence, it seems reasonable to suspect that pathogenic bacteria, which are harmful to the body, are in the world for another purpose than to cause sickness in human beings. Nature has spread acid vegetation about with a lavish hand apparently to prevent infestation of the body with pathogenic microorganisms, turning into infection of the body by these same microorganisms. Instinctually leading animals and humans to seek acid vegetation and acid liquids as protection.

Oral | Periodontal Health

Some of the pathogens found in root canals and cavitations are considered normal flora for the oral cavity. They are foreign invaders in the gut or blood stream. The question arises – how can normal oral flora be pathological? Simple. Alteration in gene expression. The oral cavity has a fluctuating pH of:

  • 6 – 6.8 exposure to fermentable carbohydrates
    • Kills Alkaline-loving-gingivitis causing bacteria
  • 9-7.1 neutral mouth
  • 7.2 – 7.4 smelling food, when hungry
    • Kills Acid-loving-cavity causing bacteria

Blood has a pH of 7.35. When bacteria pass from the oral cavity into the blood stream, bacterial genes are turned on as the pH becomes more alkaline rising above 7.0. This stimulates harmless bacteria to now produce pathogenic toxins in the blood circulating throughout your body.

Stomach acid produced in adequate quantities first responsibility is to kill Alkaline-loving bacteria. Then next would involve the chemical digestion of food. The third would be to stimulate the release of the very alkaline bile and pancreas juices causing a alkaline shift in the digestive chemistry, which kills the Acid-loving bacteria and to further facilitate the breakdown and absorption of nutrients. This flip-flop of digestive chemistry keeps the number of bacteria low in the Small Intestine preventing bacterial overgrowth.

Over the Counter and Prescription advertisements have done a good job in convincing us that the stomach over-produces stomach acid. When in reality the opposite is true. Without stomach acid to stimulate their release, pancreatic enzyme make their way into the arteries surrounding the esophagus causing the burning associated with the so-called “Acid-Reflux”.

With poor quantities of stomach acid, limited quantities of bile and pancreas juices are release. This lack of digestive chemistry production and release allows bacteria to overgrow in the small intestine. Oral bacteria swallowed with food unmolested set up their prefered environment in the small intestine. The Alkaline-loving bacteria grow unchecked hacking into the immune system and the controls for the production of digestive chemistry for their benefit.

The acidic alkaline diet food chart. Most prebiotics are high in fiber. Are the Alkaline foods High in Fiber?

‘Alkalizing’ the body can cause good bacteria to change their behavior, resulting in damage to your body. Have you ever had a friend or cousin, where their behavior changed when they got around bad influencers? The same thing happens in your gut. Alkaline-loving bacteria change the behavior of other bacteria the same way gang members change the behavior of the neighborhood they occupy. The “good” bacteria that should NOT be in the small intestine, now have a hospitable environment closer to the food supply.

How Does Alkalinity Affect Mineral Absorption?

Alkaline pH and Mineral Absorption

MINERAL ASSIMILATION and UTILIZATION is affected by pH of the gut terrain and blood. Minerals have different pH levels at which they can be assimilated into the body. Minerals on the lower end of the atomic scale can be assimilated in a wider pH range, and minerals higher up on the scale require a narrower and narrower pH range in order to be assimilated by the body. For example….

There are those that are taking Iodine supplements for their “thyroid condition”, who are also “alkalizing”. What do you think their chances are that they are assimilating the iodine?

pH control impacts every biochemical process in the body including…

ENZYMES which are part of that biochemical process. There are hundreds if not thousands of enzyme processes which take place in the body. Many are so specific that they are like complex square pegs that need to “fit” into specific square holes in order to carry out their duty. If blood or gut pH is off balance even a little, some important pegs are not “fitting” their respective slots. Enzyme function and thus life itself begins to suffer.