Blue Blockers Stimulate the Chemical of Darkness

Melatonin is the ‘‘Chemical Signal of Darkness’’. Because the duration of melatonin production is the neurochemical signal for the annual change in night length,, wearing Blue Blocker Glasses increases the duration of the “biological night”.

Melatonin Is Linked to Antioxidants in Studies

If the only studies you read are linking melatonin to anti-oxidant and that is your only point-of-view. What could possibly go wrong with artificially increasing Melatonin through supplements or Blue Blocker Glasses. Melatonin like so many other hormones are “dose-dependent”. At “normal’ levels they do their normal duties. When they are too high or too low; the response is totally different and not in a good way.

Quick Summary of Melatonin Effects on the Body

  • Visible light decreases Melatonin levels.
  • Darkness increases Melatonin levels.
    • Blue Blocker Glasses increases Melatonin levels.
  • Melatonin is produced in multiple organs in the body.
  • Naturally occurring Melatonin increases Autoimmune cytokine storms and flairs during the Fall and Winter months.
    • Wearing Blue Blocker Glasses increases the amount of naturally produced Melatonin.
  • Melatonin lowers Thyroid Stimulating Hormone (TSH).
  • Melatonin Increases Polycystic Ovarian Syndrome (PCOS).
  • Melatonin increases the Th1, Th2 immune response response to antibodies.
  • Melatonin increases Th17 immune response
  • Melatonin increases parasite reproduction.

The amount of blue light in a natural environment varies depending on the time of the day (there is more in the morning) and on the reflecting surface such as snow, grass, water, sand or cement, blue blockers which are cutting all wavelengths below 540 nm are effective in naturalistic condition albeit that proper glasses frame are made to cover all angles.

Blue Blocker Glasses cutting the blue portion of the light spectrum with orange lens glasses prevent the light-induced melatonin suppression, thereby increasing the production of melatonin. Blue Blocker Glasses represent an elegant means to increase melatonin production.

The immune system shares the same sensitivity to wavelengths as melatonin (as demonstrated by others using phase-shifting protocols,,,,, when these glasses are worn in the morning, greatly impede resynchronization of the biological clock by light.

There is a dose–response relationship between light intensity or irradiance and melatonin suppression.,,, Melatonin suppression is wavelength dependent with a peak sensitivity in the 446–477 nm (blue light) portion of the visible spectrum., Accordingly, it is possible to control the effect of light on the immune system by blocking the blue portion of the visible light.

A person’s prior light history has an impact on melatonin suppression or production., Those suffering from autoimmune disease are more likely to seclude themselves in dark rooms. Unknowingly, increasing their melatonin production and increasing their immune system reactivity.

The capacity of Blue Blocker Glasses to increase melatonin is sufficient to induce maximal melatonin suppression and about the same as encountered easily in the morning while driving.

Melatonin enhances the immune response.,, Melatonin supplementation or melatonin increasing Blue Blocker Glasses of both normal and immunocompromised individuals increases antibody responses and T helper cell activity., Melatonin administration appears to stimulate humoral immunity during early B cell development in the bone marrow. Melatonin has immune-enhancing effects and can exacerbate autoimmunity.

Melatonin Suppresses Thyroid Hormones

The hypothalamic-pituitary-thyroid axis (HPT axis) is a neuroendocrine system that regulates metabolism.  When the hypothalamus senses low circulating levels of the hormones T3 and T4, it signals to the pituitary, which then signals the thyroid gland to release T3 and T4.  T4 normally is converted to the more active T3, but T4 can also be converted to reverse T3 (rT3).  Reverse T3 works against the T3 receptor, so high levels can be detrimental.

HPT melatonin
Melatonin supplementation inhibits the TSH content in the pituitary. However, Melatonin supplementation blocks the stimulatory effect of TSH on thyroid cells responsible for the production and secretion of thyroid hormones thyroxine (T4) and triiodothyronine (T3).

During illness, profound changes may occur in the hypothalamic-pituitary-thyroid (HPT) axis. The most consistent change is a decrease in serum tri-iodothyronine (T3) level, but in severe illness, thyroxine (T4) may also decrease. The persistence of a normal or even decreased level of thyrotropin (TSH) in the face of decreased serum thyroid hormone concentrations implies a major change in HPT axis set-point regulation. Since these abnormalities of thyroid hormone concentration usually occur without any evidence of thyroid disease and disappear with recovery, they have been referred to as the `sick euthyroid syndrome’ or the `euthyroid sick syndrome’.

TSH serum levels are lower and those of free T4 are greater at night, when melatonin levels are higher, so that the response of pituitary to hypothalamic TRH and of thyroid to pituitary TSH is influenced by the pineal hormone melatonin, which alters the hypothalamic-pituitary-thyroid (HPT) axis function. Melatonin drives the molecular clockwork in the pituitary.

Melatonin & Thyroid Function

Melatonin has a suppressing action on thyroid function. Both hypothyroid and thyrotoxic patients have disturbed pineal function, which is not the case in those with weight issues. Those with hypothyroidism were found to have higher peak melatonin levels, total nighttime melatonin secretion, and urinary elimination of melatonin than normal individuals. Although thyrotoxic patients released a normal amount of melatonin during the night, their melatonin secretion peak occurs earlier in the night.

The molecular clockwork in the pituitary is strongly dependent on melatonin. Melatonin drives the rhythmic expression of clock genes in the pituitary, and the length of daytime light as well as melatonin supplements are involved in melatonin signaling.

Melatonin plays a role in the regulation of TSH release from the pituitary. Short days and long nights are correlated with decreasing levels of TSH in the pituitary. Moreover, chronic treatment with melatonin suppresses TSH release from the pituitary.

Melatonin has an inhibitory action on the Hypothalamic-pituitary-thyroid (HPT) axis. Long nights result in reduced levels of circulating thyroxin (T4). An active pineal gland produces melatonin, which inhibits thyrotrophin-releasing hormone (TRH) release from the hypothalamus. The effects of melatonin on the Hypothalamic-pituitary-thyroid (HPT) axis are similar to its effects on the Hypothalamic-pituitary-gonadal (HPG) axis.

Melatonin supplementation inhibits the TSH content in the pituitary. However, Melatonin supplementation blocks the stimulatory effect of TSH on thyroid cells responsible for the production and secretion of thyroid hormones thyroxine (T4) and triiodothyronine (T3). Free T3, T4 and TSH levels are lower with melatonin supplementation.

Melatonin is Not Just for Sleep Anymore

While most consider melatonin to be only produced by the pineal gland. It is produced throughout the body in much greater quantity (400x more in the gut). Melatonin is much more involved than previously thought. From enhancing autoimmune flairs during cytokine storms, to playing a role with infertility, melatonin and melatonin supplements used for ‘sleep problems’ enhances these conditions and not in a good way. It even plays a role in hot flashes and night chills.

If you have questions about sleep and you are having thyroid, autoimmune or infertility concerns with your health. Please contact my office.